Frederick Sebastian
Engineering | Science | Art
I am a biomedical engineer and researcher, recently completing my Ph.D. in soft tissue biomechanics at Northeastern University. My work lies at the intersection of medical technology, robotics, and data science — spanning soft-tissue biomechanics, medical device design and augmentation, soft robotic systems for neurorehabilitation, early-stage clinical trial design, and computational modeling of disease trends.
My passion for bioengineering began during my undergraduate and master’s studies at Arizona State University. While there, I studied abroad twice and discovered a deep appreciation for translational experiences. Courses like Sociology of Medicine and Health and Global Health Studies helped shape my interest in wearable technologies — with a focus on accessibility and impact. I contributed to a soft robotics project at the National University of Singapore that evolved into a commercial hand rehabilitation device for stroke patients. At Dartmouth College, I explored the role of big data in breathomics for tuberculosis detection, which further deepened my interest in data science. During my doctoral work, I also served as a systems engineer at Third Pole Therapeutics, contributing to early-stage clinical trials for an FDA-regulated nitric oxide delivery system.
My Ph.D. research centered on developing diagnostic and prognostic tools for angle-closure glaucoma — with a particular focus on the disproportionate impact the disease has on women. I leveraged skills from my Data Analytics in Engineering certificate to extract insights from metadata analysis, ex vivo animal testing, and in vivo clinical studies, supported by computational modeling techniques.
Outside of research, I’m passionate about building community and fostering collaboration. I also explore creativity through cooking, baking, writing, drawing, and food photography — pursuits that mirror my work in their shared emphasis on experimentation, precision, and process.
This site brings together the technical and creative sides of my journey. Here, you’ll find highlights from my projects, my publications, and the ideas that shape my work — both inside and outside the lab.